Gladstone is a city in Clay County, Missouri, United States and a suburb of Kansas City. The City of Gladstone is located only 10 minutes from downtown Kansas City, and 10 minutes from Kansas City International Airport. As of the 2010 census, the city population was 26,365. It is part of the Kansas City metropolitan area.

According to the United States Census Bureau, the city has a total area of 8.06 square miles The city is connected to nearby North Kansas City and Kansas City proper by Routes 1 and 283 as well as nearby U.S. Route 169, which sits less than one mile from the city's western border.

I-29 runs near the city's southernmost tip shortly after its initial break from I-35. A handful of small subdivisions maintain independent municipalities along North Oak Trafficway, a road which is host to much of the area's shopping.